Brain and Brawn: Role of Exercise-Induced Myokines

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Exercise-induced myokines and their role in chronic diseases.

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Pedersen BK, Åkerström TC, Nielsen AR, Fischer CP. Role of myokines in exercise and metabolism. J Appl Physiol 103: 1093–1098, 2007. First published March 8, 2007; doi:10.1152/japplphysiol.00080.2007.—During the past 20 yr, it has been well documented that exercise has a profound effect on the immune system. With the discovery that exercise provokes an increase in a number of cytokines, a possi...

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The Role of Exercise-Induced Myokines in Muscle Homeostasis and the Defense against Chronic Diseases

Chronic inflammation is involved in the pathogenesis of insulin resistance, atherosclerosis, neurodegeneration, and tumour growth. Regular exercise offers protection against type 2 diabetes, cardiovascular diseases, colon cancer, breast cancer, and dementia. Evidence suggests that the protective effect of exercise may to some extent be ascribed to the antiinflammatory effect of regular exercise...

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Exercise-induced myokines in health and metabolic diseases

Skeletal muscle has been emerging as a research field since the past 2 decades. Contraction of a muscle, which acts as a secretory organ, stimulates production, secretion, and expression of cytokines or other muscle fiber-derived peptides, i.e., myokines. Exercise-induced myokines influence crosstalk between different organs in an autocrine, endocrine, or paracrine fashion. Myokines are recentl...

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ژورنال

عنوان ژورنال: Journal of Obesity & Metabolic Syndrome

سال: 2019

ISSN: 2508-6235,2508-7576

DOI: 10.7570/jomes.2019.28.3.145